Irinotecan
Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.
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Adooq Products cited in reputable paper
Adooq's Irinotecan has been cited by 2 publications
Biological Activity
| Discription | Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. | ||
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Product Information
| Catalog Num | A10478 |
|---|---|
| Formula | C33H38N4O6 |
| Molecular Weight | 586.7 |
| CAS Number | 97682-44-5 |
| SMILES | CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7 |
| Synonyms | Camptosar, CPT-11 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 6 mg/mL (10.23 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.04 mL | 85.22 mL | 170.44 mL |
| 0.5 mM | 3.41 mL | 17.04 mL | 34.09 mL |
| 1 mM | 1.7 mL | 8.52 mL | 17.04 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.41 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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