Irinotecan

Catalog No.: A10478

Topoisomerase I inhibitor

Irinotecan

Irinotecan Chemical Structure

CAS NO. 97682-44-5

Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.

Availability: In stock

Package Price Qty
100 mg

Regular Price: $60.00

Special Price $48.00

200 mg

Regular Price: $100.00

Special Price $80.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.
Targets
Topo I (LoVo, HT-29 cells)
In vitro (25°C) DMSO 7 mg/mL (11.93 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.04 mL 85.22 mL 170.44 mL
0.5 mM 3.41 mL 17.04 mL 34.09 mL
1 mM 1.7 mL 8.52 mL 17.04 mL
5 mM 0.34 mL 1.7 mL 3.41 mL

*The above data is based on the productmolecular weight 586.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A10478
Actions Inhibitor
M. Wt 586.7
Formula C33H38N4O6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 97682-44-5
Synonyms Camptosar, CPT-11
SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[[email protected]@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7

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