Irinotecan
Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Adooq's Irinotecan has been cited by 3 publications
- Kerem Yalkut, .et al. , J Biomol Struct Dyn, 2024, Feb 2:1-11 PMID: 38305801
- Gils Jose, .et al. , Cancers (Basel), 2020, Oct 31;12(11):E3211 PMID: 33142721
- T Kannathasan, .et al. , Cancers (Basel), 2020, May; 12(5): 1231 PMID: 32422901
Biological Activity
| Description | Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. | |||||
|---|---|---|---|---|---|---|
| Targets |
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| Cell Research |
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Product Information
| Catalog Num | A10478 |
|---|---|
| Formula | C33H38N4O6 |
| Molecular Weight | 586.7 |
| CAS Number | 97682-44-5 |
| SMILES | CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7 |
| Synonyms | Camptosar, CPT-11 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Solubility
| In vitro (25°C) | DMSO | 6 mg/mL (10.23 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.04 mL | 85.22 mL | 170.44 mL |
| 0.5 mM | 3.41 mL | 17.04 mL | 34.09 mL |
| 1 mM | 1.7 mL | 8.52 mL | 17.04 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.41 mL |
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution.This equation is commonly abbreviated as: C1V1 = C2V2
