Irinotecan

Catalog No.: A10478
Topoisomerase I inhibitor
Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.
Grouped product items
Product Name Price Stock Qty
Irinotecan 100mg
$60.00
In stock
Irinotecan 200mg
$100.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Irinotecan has been cited by 2 publications
  • Gils Jose, .et al. , Cancers (Basel), 2020, Oct 31;12(11):E3211 PMID: 33142721
  • T Kannathasan, .et al. , Cancers (Basel), 2020, May; 12(5): 1231 PMID: 32422901
  • Biological Activity
    Discription Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.
    Targets
    Target Value
    Product Information
    Catalog Num A10478
    Formula C33H38N4O6
    Molecular Weight 586.7
    CAS Number 97682-44-5
    SMILES CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)[C@@]5(CC)O)OC(=O)N6CCC(CC6)N7CCCCC7
    Synonyms Camptosar, CPT-11
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 6 mg/mL (10.23 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.04 mL 85.22 mL 170.44 mL
    0.5 mM 3.41 mL 17.04 mL 34.09 mL
    1 mM 1.7 mL 8.52 mL 17.04 mL
    5 mM 0.34 mL 1.7 mL 3.41 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

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