11beta-Hydroxyprogesterone is an endogenous metabolite that functions as a potent inhibitor of 11β-Hydroxysteroid dehydrogenase. It also activates the human mineralocorticoid receptor in COS-7 cells with an effective dose (ED50) of 10 nM. This compound is valuable for research in steroid metabolism and endocrine regulation. Its dual activity makes it a useful tool for studying hormone signaling pathways and their physiological implications.
11beta-Hydroxyprogesterone is an endogenous metabolite that functions as a potent inhibitor of 11β-Hydroxysteroid dehydrogenase. It also activates the human mineralocorticoid receptor in COS-7 cells with an effective dose (ED50) of 10 nM. This compound is valuable for research in steroid metabolism and endocrine regulation. Its dual activity makes it a useful tool for studying hormone signaling pathways and their physiological implications.
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