Fig. 1 · Structure
Documents & Downloads
11beta-Hydroxyprogesterone
Cat. No.
A15700
CAS
600-57-7
Endogenous Metabolite
11beta-Hydroxyprogesterone is an endogenous metabolite that functions as a potent inhibitor of 11β-Hydroxysteroid dehydrogenase. It also activates the human mineralocorticoid receptor in COS-7 cells with an effective dose (ED50) of 10 nM. This compound is valuable for research in steroid metabolism and endocrine regulation. Its dual activity makes it a useful tool for studying hormone signaling pathways and their physiological implications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 600-57-7 |
| Applications | Endogenous Metabolite |
| Formula | C21H30O3 |
| Molecular Weight | 330.47 |
| Synonyms | 11β-Hydroxyprogesterone |
| SMILES | C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@@](C)([C@@H](C(C)=O)CC4)C[C@@H]3O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.