12-Oxocalanolide A is a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an IC50 of 2.8 μM and an EC50 of 12 μM. This compound serves as an analogue of Calanolide, demonstrating significant antiviral activity against human immunodeficiency virus type 1. It is valuable for research in virology and the development of anti-HIV therapeutics.
12-Oxocalanolide A is a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an IC50 of 2.8 μM and an EC50 of 12 μM. This compound serves as an analogue of Calanolide, demonstrating significant antiviral activity against human immunodeficiency virus type 1. It is valuable for research in virology and the development of anti-HIV therapeutics.
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