(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate functions as a non-cleavable linker for antibody-drug conjugates (ADCs), facilitating the formation of stable conjugates for targeted cancer therapies. This compound serves as an effective alkyl chain-based PROTAC linker, allowing for the development of proteolysis-targeting chimeras that can induce selective degradation of specific proteins in research studies. Its robust mechanism makes it a valuable tool in the fields of drug development and targeted therapy.
(2R,4R)-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate functions as a non-cleavable linker for antibody-drug conjugates (ADCs), facilitating the formation of stable conjugates for targeted cancer therapies. This compound serves as an effective alkyl chain-based PROTAC linker, allowing for the development of proteolysis-targeting chimeras that can induce selective degradation of specific proteins in research studies. Its robust mechanism makes it a valuable tool in the fields of drug development and targeted therapy.
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