3β,7β-Dihydroxy-5-cholestenoic acid is an endogenous metabolite that plays a crucial role in lipid metabolism. Elevated levels of this C27 acid have been associated with Niemann-Pick type C and Niemann-Pick type B diseases, contributing to neuronal toxicity, particularly in oculomotor neurons. This compound is produced through the enzymatic action of hydroxysteroid 11-β dehydrogenase 1 on 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid and is valuable for research into lipid-related disorders and neurodegenerative diseases.
3β,7β-Dihydroxy-5-cholestenoic acid is an endogenous metabolite that plays a crucial role in lipid metabolism. Elevated levels of this C27 acid have been associated with Niemann-Pick type C and Niemann-Pick type B diseases, contributing to neuronal toxicity, particularly in oculomotor neurons. This compound is produced through the enzymatic action of hydroxysteroid 11-β dehydrogenase 1 on 3β-hydroxy-7-oxocholest-5-en-(25R)26-oic acid and is valuable for research into lipid-related disorders and neurodegenerative diseases.
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