Fig. 1 · Structure
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4-Epidoxycycline
Antitumor Agents
4-Epidoxycycline is a hepatically metabolized derivative of the antibiotic doxycycline, specifically targeting antitumor applications. This compound modulates HER2 gene expression both in vitro and in vivo, demonstrating potent antitumor efficacy. Notably, 4-Epidoxycycline has achieved over 95% tumor regression rates in various tumor models, underscoring its potential as a significant therapeutic agent in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 6543-77-7 |
| Applications | Antitumor Agents |
| Formula | C22H24N2O8 |
| Molecular Weight | 444.43 |
| SMILES | O=C(C(C1=O)=C(O)[C@H](N(C)C)[C@]2([H])[C@@H](O)[C@]3([H])[C@@H](C)C4=C(C(C3=C(O)[C@@]21O)=O)C(O)=CC=C4)N |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.