4-Hydroperoxy cyclophosphamide is an active metabolite of the precursor cyclophosphamide, primarily targeting DNA cross-linking. This compound induces T cell apoptosis through a caspase-independent mechanism and can activate the mitochondrial death pathway via reactive oxygen species (ROS) generation. It is valuable for research applications in studying mechanisms underlying rheumatoid arthritis and other autoimmune diseases.
4-Hydroperoxy cyclophosphamide is an active metabolite of the precursor cyclophosphamide, primarily targeting DNA cross-linking. This compound induces T cell apoptosis through a caspase-independent mechanism and can activate the mitochondrial death pathway via reactive oxygen species (ROS) generation. It is valuable for research applications in studying mechanisms underlying rheumatoid arthritis and other autoimmune diseases.
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