4′-O-Methylglabridin is an apoptosis inducer that disrupts the cell cycle and exhibits antioxidant and cytotoxic activities against cancer cells. It has been shown to inhibit a range of cancer cell lines, including liver, breast, and colorectal cancers, by reducing phosphorylated Rb and p21 protein levels, leading to an accumulation of cells in the subG1 and G2/M phases. Furthermore, 4′-O-Methylglabridin triggers caspase-dependent apoptosis through the release of cytochrome C and activation of caspase-9. Its antioxidant properties also include the inhibition of lipid peroxidation and prevention of LDL oxidation. This compound is valuable for research in cancer biology and atherosclerosis.
4′-O-Methylglabridin is an apoptosis inducer that disrupts the cell cycle and exhibits antioxidant and cytotoxic activities against cancer cells. It has been shown to inhibit a range of cancer cell lines, including liver, breast, and colorectal cancers, by reducing phosphorylated Rb and p21 protein levels, leading to an accumulation of cells in the subG1 and G2/M phases. Furthermore, 4′-O-Methylglabridin triggers caspase-dependent apoptosis through the release of cytochrome C and activation of caspase-9. Its antioxidant properties also include the inhibition of lipid peroxidation and prevention of LDL oxidation. This compound is valuable for research in cancer biology and atherosclerosis.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
