(4′R)-TGR5 Receptor Agonist 4

Catalog No.: A60395
R enantiomer of TGR5 Receptor Agonist 4
(4′R)-TGR5 Receptor Agonist 4 is an R enantiomer that selectively targets the TGR5 receptor, a bile acid receptor essential in metabolic regulation. It exhibits high potency with EC50 values of 2 nM for human TGR5 and 3 nM for mouse TGR5. This compound is important for studies related to hypoglycemia and weight management, facilitating research into therapeutic strategies for metabolic disorders.
Grouped product items
Size Price Stock Qty
1mg
$170.00
In stock
5mg
$440.00
In stock
10mg
$750.00
In stock
25mg
$1,495.00
In stock
50mg
$2,335.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(4′R)-TGR5 Receptor Agonist 4 is an R enantiomer that selectively targets the TGR5 receptor, a bile acid receptor essential in metabolic regulation. It exhibits high potency with EC50 values of 2 nM for human TGR5 and 3 nM for mouse TGR5. This compound is important for studies related to hypoglycemia and weight management, facilitating research into therapeutic strategies for metabolic disorders.
Product Information
Catalog NumA60395
FormulaC25H27ClN2O5
Molecular Weight470.95
CAS Number1872436-55-9
SMILESCOC(C=CC=C1)=C1COC(C([C@@H](C2=CN=C(Cl)C=C2)C3)=C(C)N(C[C@H]4CCCO4)C3=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2