(4S)-4-Hydroxy-D-proline methyl ester hydrochloride functions as a non-cleavable linker in the development of antibody-drug conjugates (ADCs). This compound exhibits key biological activity by facilitating stable covalent attachment between antibodies and cytotoxic agents, enhancing the therapeutic efficacy of ADCs. Additionally, its alkyl chain structure allows for application as a PROTAC linker, aiding in the design and synthesis of proteolysis-targeting chimeras.
(4S)-4-Hydroxy-D-proline methyl ester hydrochloride functions as a non-cleavable linker in the development of antibody-drug conjugates (ADCs). This compound exhibits key biological activity by facilitating stable covalent attachment between antibodies and cytotoxic agents, enhancing the therapeutic efficacy of ADCs. Additionally, its alkyl chain structure allows for application as a PROTAC linker, aiding in the design and synthesis of proteolysis-targeting chimeras.
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