5-Fluorouracil-13C,15N2 is a stable isotope-labeled derivative of 5-Fluorouracil (5-FU), an analogue of uracil known for its potent antitumor activity. It primarily targets thymidylate synthetase, leading to a significant reduction in intracellular dTTP levels, thereby disrupting pyrimidine synthesis and promoting apoptosis. This compound is valuable in cancer research and may also provide insights into mechanisms of viral inhibition, including activity against HIV.
5-Fluorouracil-13C,15N2 is a stable isotope-labeled derivative of 5-Fluorouracil (5-FU), an analogue of uracil known for its potent antitumor activity. It primarily targets thymidylate synthetase, leading to a significant reduction in intracellular dTTP levels, thereby disrupting pyrimidine synthesis and promoting apoptosis. This compound is valuable in cancer research and may also provide insights into mechanisms of viral inhibition, including activity against HIV.
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