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Fluorouracil (Adrucil)

Fluorouracil (Adrucil) Chemical Structure

CAS NO. 51-21-8

Fluorouracil (Adrucil) is a suicide inhibitor and works through irreversible inhibition of thymidylate synthase.

Availability: In stock

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200 mg
10mM * 1mL in DMSO
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Warning WARNING: Attention California Residents: This product can expose you to chemicals including Fluorouracil (Adrucil) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Fluorouracil (Adrucil) is a suicide inhibitor and works through irreversible inhibition of thymidylate synthase.
Thymidylate synthase (Tumor cells)
In vitro (25°C) DMSO 22 mg/mL (169.12 mM)
Water Insoluble
Ethanol Insoluble
In vivo saline (warming) 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 76.86 mL 384.32 mL 768.64 mL
0.5 mM 15.37 mL 76.86 mL 153.73 mL
1 mM 7.69 mL 38.43 mL 76.86 mL
5 mM 1.54 mL 7.69 mL 15.37 mL

*The above data is based on the productmolecular weight 130.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10042
Actions Inhibitor
CAS No. 51-21-8
Formula C4H3FN2O2
M. Wt 130.1
Purity >98%
Synonyms Adrucil, 5-FU, Carac, Efudex, Fluoroplex

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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