Important Notice: For research use only. We do not sell to patients.
WARNING: Attention California Residents: This product can expose you to chemicals including Fluorouracil (Adrucil) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Adi Jacob Berger, .et al. , Nat Cancer, 2021, 2, 1055-1070 PMID: 35121883
Biological Activity
Discription
Fluorouracil (Adrucil) is a suicide inhibitor and works through irreversible inhibition of thymidylate synthase.
Targets
Target
Value
Cell Research
Cell Line
Type
Value
Description
References
Product Information
Catalog Num
A10042
Formula
C4H3FN2O2
Molecular Weight
130.1
CAS Number
51-21-8
SMILES
C1=C(C(=O)NC(=O)N1)F
Synonyms
Adrucil, 5-FU, Carac, Efudex, Fluoroplex
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
22 mg/mL (169.12 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
saline (warming)
9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
WARNING: Attention California Residents: This product can expose you to chemicals including Fluorouracil (Adrucil) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
