Important Notice: For research use only. We do not sell to patients.
WARNING: Attention California Residents: This product can expose you to chemicals including Fluorouracil (Adrucil) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
Adi Jacob Berger, .et al. , Nat Cancer, 2021, 2, 1055-1070 PMID: 35121883
Biological Activity
Discription
Fluorouracil (Adrucil) is a suicide inhibitor and works through irreversible inhibition of thymidylate synthase.
Targets
Target
Value
Product Information
Catalog Num
A10042
Formula
C4H3FN2O2
Molecular Weight
130.1
CAS Number
51-21-8
SMILES
C1=C(C(=O)NC(=O)N1)F
Synonyms
Adrucil, 5-FU, Carac, Efudex, Fluoroplex
Storage
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C)
DMSO
22 mg/mL (169.12 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
saline (warming)
9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
WARNING: Attention California Residents: This product can expose you to chemicals including Fluorouracil (Adrucil) , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov
