5-Fluorouracil-15N2 is a stable isotope-labeled analogue of the chemotherapeutic agent 5-Fluorouracil (5-FU). It primarily targets thymidylate synthetase, inhibiting pyrimidine synthesis and leading to decreased intracellular dTTP levels, which induces apoptosis in cancer cells. Additionally, it has been noted for its potential to serve as a chemical sensitizer and exhibits inhibitory effects on HIV. This compound is valuable for research applications in cancer therapy and HIV studies.
5-Fluorouracil-15N2 is a stable isotope-labeled analogue of the chemotherapeutic agent 5-Fluorouracil (5-FU). It primarily targets thymidylate synthetase, inhibiting pyrimidine synthesis and leading to decreased intracellular dTTP levels, which induces apoptosis in cancer cells. Additionally, it has been noted for its potential to serve as a chemical sensitizer and exhibits inhibitory effects on HIV. This compound is valuable for research applications in cancer therapy and HIV studies.
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