Finasteride-d9 is a deuterium-labeled derivative of Finasteride, a potent competitive inhibitor of 5α-reductase, exhibiting an IC50 of 4.2 nM for the type II isoform. This compound demonstrates significantly greater affinity for type II 5α-reductase, being approximately 100 times more selective than for type I. Finasteride-d9 is valuable in research applications focused on benign prostatic hyperplasia (BPH) and androgenic alopecia, facilitating studies on the pharmacokinetics and metabolism of its parent compound.
Finasteride-d9 is a deuterium-labeled derivative of Finasteride, a potent competitive inhibitor of 5α-reductase, exhibiting an IC50 of 4.2 nM for the type II isoform. This compound demonstrates significantly greater affinity for type II 5α-reductase, being approximately 100 times more selective than for type I. Finasteride-d9 is valuable in research applications focused on benign prostatic hyperplasia (BPH) and androgenic alopecia, facilitating studies on the pharmacokinetics and metabolism of its parent compound.
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