5-(N,N-Hexamethylene)-amiloride

Catalog No.: A18891

Na+/H+ exchanger inhibitor

5-(N,N-Hexamethylene)-amiloride

5-(N,N-Hexamethylene)-amiloride Chemical Structure

CAS NO. 1428-95-1

5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells.

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250 mg
$45.00
500 mg
$90.00
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Biological Activity

5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.07 mL 160.37 mL 320.75 mL
0.5 mM 6.41 mL 32.07 mL 64.15 mL
1 mM 3.21 mL 16.04 mL 32.07 mL
5 mM 0.64 mL 3.21 mL 6.41 mL

*The above data is based on the productmolecular weight 311.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18891
Actions Inhibitor
CAS No. 1428-95-1
Formula C12H18ClN7O
M. Wt 311.77
Purity >98%
Synonyms 0
SMILES O=C(C1=NC(Cl)=C(N2CCCCCC2)N=C1N)NC(N)=N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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