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Biological Activity
5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.07 mL | 160.37 mL | 320.75 mL |
| 0.5 mM | 6.41 mL | 32.07 mL | 64.15 mL |
| 1 mM | 3.21 mL | 16.04 mL | 32.07 mL |
| 5 mM | 0.64 mL | 3.21 mL | 6.41 mL |
*The above data is based on the productmolecular weight 311.77. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18891 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1428-95-1 |
| Formula | C12H18ClN7O |
| M. Wt | 311.77 |
| Purity | >98% |
| Synonyms | 0 |
| SMILES | O=C(C1=NC(Cl)=C(N2CCCCCC2)N=C1N)NC(N)=N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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