Fig. 1 · Structure
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5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol
Antimicrobial Agent
5-(Pyridin-4-yl)-1,3,4-oxadiazole-2-thiol serves as an antimicrobial agent with targeted activity against Escherichia coli and Staphylococcus epidermidis, demonstrating minimum inhibitory concentrations of 8 and 4 μg/mL, respectively. Additionally, this compound exhibits notable antioxidant properties, evidenced by an IC50 value of 17.47 μM in the DPPH free radical-scavenging assay. Its dual action makes it a valuable reagent for research in antimicrobial activity and oxidative stress studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 15264-63-8 |
| Applications | Antimicrobial Agent |
| Formula | C7H5N3OS |
| Molecular Weight | 179.20 |
| SMILES | C1=C(C=CN=C1)C2=NN=C(O2)S |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.