Signaling Pathway
6-Diazo-5-oxo-L-nor-Leucine is a glutamine antagonist that shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells.
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| Discription | 6-Diazo-5-oxo-L-nor-Leucine is a glutamine antagonist that shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. |
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| Catalog Num | A20846 |
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| Formula | C6H9N3O3 |
| Molecular Weight | 171.15 |
| CAS Number | 157-03-9 |
| SMILES | C(CC(=O)C=[N+]=[N-])C(C(=O)O)N |
| Synonyms | Diazooxonorleucine, 6-Diazo-5-oxo-L-nor-Leucine, L-6-Diazo-5-oxonorleucine, DON |
| In vitro | DMSO | Insoluble | |
| Water | 25 mg/mL (146.07 mM; Need ultrasonic) | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 58.43 mL | 292.14 mL | 584.28 mL |
| 0.5 mM | 11.69 mL | 58.43 mL | 116.86 mL |
| 1 mM | 5.84 mL | 29.21 mL | 58.43 mL |
| 5 mM | 1.17 mL | 5.84 mL | 11.69 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
