6α-Hydroxy Paclitaxel-d5 is a stable isotope-labeled form of 6α-Hydroxy paclitaxel, a significant metabolite of Paclitaxel (PTX) produced by the liver enzyme CYP2C8. This compound exhibits bone marrow toxicity; however, it has been shown to enhance the cytotoxic effects of paclitaxel against leukemia cells while minimizing cellular toxicity. As such, 6α-Hydroxy paclitaxel-d5 is an important reagent for research in leukemia and related cancer therapies.
6α-Hydroxy Paclitaxel-d5 is a stable isotope-labeled form of 6α-Hydroxy paclitaxel, a significant metabolite of Paclitaxel (PTX) produced by the liver enzyme CYP2C8. This compound exhibits bone marrow toxicity; however, it has been shown to enhance the cytotoxic effects of paclitaxel against leukemia cells while minimizing cellular toxicity. As such, 6α-Hydroxy paclitaxel-d5 is an important reagent for research in leukemia and related cancer therapies.
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