7,3',4'-Tri-O-methylluteolin is a flavonoid that acts as an anti-inflammatory agent by inhibiting soybean lipoxygenase (LOX), with an IC50 value of 23.97 µg/mL. This compound demonstrates significant anti-inflammatory effects in LPS-induced RAW 264.7 macrophages and has been shown to inhibit the MDM2-p53 binding, thereby inducing apoptosis in MCF-7 breast cancer cells. Furthermore, 7,3',4'-Tri-O-methylluteolin exhibits antioxidant, antifungal, and antitrypanosomal properties, making it valuable for various biological research applications.
7,3',4'-Tri-O-methylluteolin is a flavonoid that acts as an anti-inflammatory agent by inhibiting soybean lipoxygenase (LOX), with an IC50 value of 23.97 µg/mL. This compound demonstrates significant anti-inflammatory effects in LPS-induced RAW 264.7 macrophages and has been shown to inhibit the MDM2-p53 binding, thereby inducing apoptosis in MCF-7 breast cancer cells. Furthermore, 7,3',4'-Tri-O-methylluteolin exhibits antioxidant, antifungal, and antitrypanosomal properties, making it valuable for various biological research applications.
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