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7-Hydroxycoumarinyl arachidonate

PLA2 Fluorogenic Substrate

7-Hydroxycoumarinyl arachidonate is a fluorogenic substrate for cytosolic phospholipase A2 (PLA2) and monoacylglycerol lipase (MAGL). Upon hydrolysis, it generates arachidonic acid (AA) and the highly fluorescent product 7-hydroxyl coumarin (7-HC). The production of 7-HC can be quantitatively assessed using a fluorometer, making this compound valuable for studies investigating the enzymatic activity of PLA2 and MAGL in various biological contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Substrate
CAS Number	161180-11-6
Applications	PLA2 Fluorogenic Substrate
Formula	C₂₉H₃₆O₄
Molecular Weight	448.59
Synonyms	7-HCA; Umbelliferyl Arachidonate; 7-HC-arachidonate
SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(OC1=CC=C2C=CC(OC2=C1)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.