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8-Deazafolic acid

Antimicrobial Drug

8-Deazafolic acid is an antimicrobial agent that targets folate-dependent bacteria such as Streptococcus faecium (ATCC 8043) and Lactobacillus casei (ATCC 74691). This compound demonstrates potent activity against lymphoid leukemia L1210 in murine models, making it a valuable tool for research in microbiology and cancer biology. Its specific targeting of folate metabolism pathways offers insights into microbial resistance mechanisms and potential therapeutic applications in treating bacterial infections and malignancies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	51989-25-4
Applications	Antimicrobial Drug
Formula	C₂₀H₂₀N₆O₆
Molecular Weight	440.41
SMILES	O=C(CC[C@H](NC(C1=CC=C(C=C1)NCC2=CC=C(NC(N)=NC3=O)C3=N2)=O)C(O)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.