Fig. 1 · Structure
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A-350619 hydrochloride
sGC Activator
A-350619 hydrochloride is a soluble guanylate cyclase (sGC) activator that enhances intracellular cGMP levels. This compound exhibits significant biological activity in the modulation of vasodilation and neurotransmission, making it relevant for research into erectile dysfunction and related vascular disorders. Its role in enhancing sGC activity makes it a valuable tool for investigating therapeutic strategies targeting nitric oxide signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1217201-17-6 |
| Applications | sGC Activator |
| Formula | C21H26Cl2N2OS |
| Molecular Weight | 425.41 |
| SMILES | O=C(NCCCCN(C)C)/C=C/C1=C(SC2=CC=C(C=C2)Cl)C=CC=C1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.