Fig. 1 · Structure

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A-350619

sGC Activator

A-350619 is a selective activator of soluble guanylate cyclase (sGC), resulting in elevated intracellular levels of cyclic guanosine monophosphate (cGMP). This compound has been demonstrated to significantly induce penile erection, highlighting its potential therapeutic applications in erectile dysfunction research. Further studies may explore its effects on vascular smooth muscle relaxation and other cGMP-related biological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Activator
CAS Number 538368-27-3
Applications sGC Activator
Formula C21H25ClN2OS
Molecular Weight 388.95
SMILES
O=C(NCCCCN(C)C)/C=C/C1=CC=CC=C1SC2=CC=C(Cl)C=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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