A-350619

Catalog No.: A60895
sGC Activator
A-350619 is a selective activator of soluble guanylate cyclase (sGC), resulting in elevated intracellular levels of cyclic guanosine monophosphate (cGMP). This compound has been demonstrated to significantly induce penile erection, highlighting its potential therapeutic applications in erectile dysfunction research. Further studies may explore its effects on vascular smooth muscle relaxation and other cGMP-related biological processes.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionA-350619 is a selective activator of soluble guanylate cyclase (sGC), resulting in elevated intracellular levels of cyclic guanosine monophosphate (cGMP). This compound has been demonstrated to significantly induce penile erection, highlighting its potential therapeutic applications in erectile dysfunction research. Further studies may explore its effects on vascular smooth muscle relaxation and other cGMP-related biological processes.
Product Information
Catalog NumA60895
FormulaC21H25ClN2OS
Molecular Weight388.95
CAS Number538368-27-3
SMILESO=C(NCCCCN(C)C)/C=C/C1=CC=CC=C1SC2=CC=C(Cl)C=C2
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