α-Synuclein Inhibitor 9 is a selective inhibitor that targets α-synuclein, a protein implicated in neurodegenerative disorders. This compound binds to specific cavities within mature α-synuclein fibrils, effectively disrupting β-sheet formation and inhibiting the aggregation of the A53T α-synuclein variant. It demonstrates neuroprotective effects, improves brain functional connectivity, and alleviates motor dysfunction. This reagent is valuable for research focused on Parkinson's disease and related pathologies.
α-Synuclein Inhibitor 9 is a selective inhibitor that targets α-synuclein, a protein implicated in neurodegenerative disorders. This compound binds to specific cavities within mature α-synuclein fibrils, effectively disrupting β-sheet formation and inhibiting the aggregation of the A53T α-synuclein variant. It demonstrates neuroprotective effects, improves brain functional connectivity, and alleviates motor dysfunction. This reagent is valuable for research focused on Parkinson's disease and related pathologies.
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