Fig. 1 · Structure

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AAA-10

BSH Inhibitor

AAA-10 is a potent bile salt hydrolase (BSH) inhibitor, targeting gut bacterial enzymes with IC50 values of 10 nM for Bacteroides theta rBSH and 80 nM for Bifidobacterium longum rBSH. This compound is useful in research focused on gut microbiota modulation and bile acid metabolism. Its oral bioactivity makes it an ideal tool for investigating the role of BSH in gastrointestinal health and disease.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2758171-70-7
Applications BSH Inhibitor
Formula C25H41FO5S
Molecular Weight 472.65
SMILES
C[C@H](CCC(CF)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](OS(=O)(O)=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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