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Biological Activity
ABT-046 is a potent, selective, and orally bioavailable Diacylglycerol acyltransferase 1 (DGAT-1 ) inhibitor (IC50= 8 nM).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.54 mL | 142.69 mL | 285.38 mL |
| 0.5 mM | 5.71 mL | 28.54 mL | 57.08 mL |
| 1 mM | 2.85 mL | 14.27 mL | 28.54 mL |
| 5 mM | 0.57 mL | 2.85 mL | 5.71 mL |
*The above data is based on the productmolecular weight 350.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14984 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1031336-60-3 |
| Formula | C20H22N4O2 |
| M. Wt | 350.41 |
| Purity | >98% |
| Synonyms | DGAT-1 inhibitor, ABT 046,ABT046 |
| SMILES | C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)C3=C(N4C(=CC=N4)N=C3)N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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