Fig. 1 · Structure
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Ac-Atovaquone
Cytochrome bc1 Inhibitor
Ac-Atovaquone is a potent inhibitor of the cytochrome bc1 complex, functioning as an ester-linked acetyl derivative of atovaquone. This compound exhibits significant biological activity against malaria, making it valuable for research focused on the mechanisms of malaria pathogenesis and potential therapeutic interventions. Its inhibition of the cytochrome bc1 complex contributes to its role in studying mitochondrial function and identifying novel anti-malarial strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 129700-44-3 |
| Applications | Cytochrome bc1 Inhibitor |
| Formula | C24H21ClO4 |
| Molecular Weight | 408.87 |
| SMILES | O=C1C([C@H]2CC[C@H](C3=CC=C(Cl)C=C3)CC2)=C(OC(C)=O)C(C4=CC=CC=C41)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.