Fig. 1 · Structure
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Ac-LETD-AFC
Caspase-8 Fluorogenic Substrate
Ac-LETD-AFC is a fluorogenic substrate specifically designed for the quantification of caspase-8 activity. This compound enables the measurement of caspase-8-mediated proteolytic activity, serving as a valuable tool for studying cancer cell apoptosis and oxidative stress metabolism. Its application supports research in cellular signaling pathways related to programmed cell death and various stress responses.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 210345-02-1 |
| Applications | Caspase-8 Fluorogenic Substrate |
| Formula | C31H38F3N5O12 |
| Molecular Weight | 729.65 |
| SMILES | C(F)(F)(F)C=1C=2C(=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CC(O)=O)=O)=CC2)OC(=O)C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.