Fig. 1 · Structure
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ACHN-975 TFA
LpxC Inhibitor
ACHN-975 TFA is a selective inhibitor of the enzyme LpxC, demonstrating subnanomolar inhibitory activity. This compound effectively targets a variety of gram-negative bacterial strains, exhibiting low minimum inhibitory concentration (MIC) values of ≤1 μg/mL. ACHN-975 TFA is a valuable tool for research focused on bacterial resistance mechanisms and the development of novel antimicrobial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1410809-37-8 |
| Applications | LpxC Inhibitor |
| Formula | C22H24F3N3O6 |
| Molecular Weight | 483.44 |
| SMILES | O=C(N[C@H](C(NO)=O)C(C)(N)C)C1=CC=C(C#CC#C[C@H]2[C@H](CO)C2)C=C1.O=C(O)C(F)(F)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.