Documents & Downloads

AcrB-IN-4

AcrB Efflux Pump Inhibitor

AcrB-IN-4 is a potent inhibitor of the AcrB efflux pump, which plays a significant role in bacterial multidrug resistance. This compound enhances the effectiveness of antibiotics by preventing the efflux of Nile Red, a known substrate of AcrB. Importantly, AcrB-IN-4 does not compromise the integrity of the bacterial outer membrane and exhibits low toxicity in nematode models, making it a valuable tool for research into bacterial resistance mechanisms and antibiotic efficacy.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2890177-95-2
Applications	AcrB Efflux Pump Inhibitor
Formula	C₂₉H₃₄N₂O₄S
Molecular Weight	506.66
SMILES	O=C(N1CCOCC1)C2=CC3=C(C4=C2CCC(C)(C)O4)C=CC=C3OCCCSC5=CC=C(C=C5)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.