Actinomycin D

Actinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram negative bacteria.
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Product Name Price Stock Qty
Actinomycin D 10mg
$80.00
In stock
Actinomycin D 25mg
$200.00
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Actinomycin D 50mg
$280.00
In stock
Actinomycin D 100mg
$480.00
In stock
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Important Notice: For research use only. We do not sell to patients.

Prop65 Warning  WARNING: Attention California Residents: This product can expose you to chemicals including Actinomycin D , which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov

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Adooq Products cited in reputable paper
Adooq's Actinomycin D has been cited by 3 publications
  • Zegui N, .et al. , Cancer Research, 2022, FEBRUARY 22 PMID: 35502544
  • Lina Gu, .et al. , Molecular Cancer, 2022, 21:217
  • Chauhan D, .et al. , Cell Rep, 2018, Nov 27;25(9):2354-2368.e5 PMID: 30485805
  • Biological Activity
    Discription Actinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram negative bacteria.
    Product Information
    Catalog Num A13239
    Formula C62H86N12O16
    Molecular Weight 1255.4
    CAS Number 50-76-0
    SMILES CC1C(C(=O)NC(C(=O)N2CCCC2C(=O)N(CC(=O)N(C(C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)NC6C(OC(=O)C(N(C(=O)CN(C(=O)C7CCCN7C(=O)C(NC6=O)C(C)C)C)C)C(C)C)C)N)C
    Synonyms Actinomycin-D
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 91 mg/mL (72.48 mM)
    Water Insoluble
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 7.97 mL 39.83 mL 79.66 mL
    0.5 mM 1.59 mL 7.97 mL 15.93 mL
    1 mM 0.8 mL 3.98 mL 7.97 mL
    5 mM 0.16 mL 0.8 mL 1.59 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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