Fig. 1 · Structure
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AGN 192403 hydrochloride
Imidazoline-1 Receptor Antagonist
AGN 192403 hydrochloride is a potent and selective antagonist of the imidazoline-1 receptor, exhibiting a Ki value of 42 nM. This compound functions as a TMED9 inhibitor and demonstrates protective effects against oxidative and mitochondrial inhibitor-induced cytotoxicity in astrocytes. Additionally, AGN 192403 hydrochloride reduces the proliferation and migration of differentiated glioma tumor cells, making it a valuable tool for research related to glioma tumors and various neurological diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1021868-90-5 |
| Applications | Imidazoline-1 Receptor Antagonist |
| Formula | C10H20ClN |
| Molecular Weight | 189.73 |
| Synonyms | BRD4780 hydrochloride |
| SMILES | CC(C)[C@@H]1[C@@H](N)[C@H]2CC[C@@H]1C2.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.