Fig. 1 · Structure

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AGN 192403

Imidazoline-1 Receptor Antagonist

AGN 192403 is a potent and selective imidazoline-1 receptor antagonist with a Ki value of 42 nM. This compound also acts as a TMED9 inhibitor and demonstrates protective effects against oxidative and mitochondrial inhibitor-induced cytotoxicity in astrocytes. Additionally, AGN 192403 inhibits the proliferation and migration of differentiated glioma tumor cells. It is a valuable reagent for research related to glioma tumors and various neurological diseases.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 175521-95-6
Applications Imidazoline-1 Receptor Antagonist
Formula C10H19N
Molecular Weight 153.26
Synonyms BRD4780
SMILES
CC([C@H]1[C@@]2([H])C[C@@](CC2)([H])[C@@H]1N)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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