Fig. 1 · Structure
Documents & Downloads
Alkyne-PEG4-maleimide
PROTAC Linker
Alkyne-PEG4-maleimide is a PEG-based linker designed for use in PROTAC (proteolysis-targeting chimera) synthesis. This compound features an alkyne functional group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application as a linker facilitates the creation of bifunctional molecules for targeted protein degradation studies and other advanced research applications in chemical biology.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1609651-90-2 |
| Applications | PROTAC Linker |
| Formula | C18H26N2O7 |
| Molecular Weight | 382.41 |
| SMILES | O=C(C=CC1=O)N1CCC(NCCOCCOCCOCCOCC#C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.