Alkyne-Val-Cit-PAB-OH

Catalog No.: A43393
ADC Linker
Alkyne-Val-Cit-PAB-OH is a cleavable linker designed for antibody-drug conjugates (ADCs). This compound facilitates the selective release of drug payloads within target cells, enhancing therapeutic efficacy while minimizing off-target effects. Its hydrophilic properties and favorable stability make it suitable for various ADC applications, including cancer therapy and targeted drug delivery research.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAlkyne-Val-Cit-PAB-OH is a cleavable linker designed for antibody-drug conjugates (ADCs). This compound facilitates the selective release of drug payloads within target cells, enhancing therapeutic efficacy while minimizing off-target effects. Its hydrophilic properties and favorable stability make it suitable for various ADC applications, including cancer therapy and targeted drug delivery research.
Product Information
Catalog NumA43393
FormulaC24H35N5O5
Molecular Weight473.57
CAS Number2748039-76-9
SMILESOCC(C=C1)=CC=C1NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCCC#C)=O)=O)=O
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