alpha-Amyloid Precursor Protein Modulator

Catalog No.: A13094

alpha-Amyloid Precursor Protein Modulator

alpha-Amyloid Precursor Protein Modulator Chemical Structure

CAS NO. 497259-23-1

alpha-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblas.

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Package Price Qty
2 mg
$180.00
5 mg
$350.00
10 mg
$650.00
25 mg
$1,200.00
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Biological Activity

alpha-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator (Ki = 11.9 nM for PKCα) that efficiently enhances non-amyloidogenic α-processing of amyloid precursor protein (APP) even at 100 nM in human fibroblas.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL

*The above data is based on the productmolecular weight 501.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13094
M. Wt 501.5
Formula C27H30F3N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 497259-23-1
Synonyms PKC Activator V
SMILES CC(C)[[email protected]]1C(=O)N[[email protected]@H](CC2=C(N1C)C=CC(=C2)NC(=O)/C=C/C=C/C3=CC=C(C=C3)C(F)(F)F)CO

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