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- Seda Onder, .et al. Chlorpyrifos oxon crosslinking of amyloid beta 42 peptides is a new route for generation of self-aggregating amyloidogenic oligomers that promote Alzheimer's disease, Chem Biol Interact, 2022, Aug 25;363:110029 PMID: 35779611
- Seham S El-Hawary, .et al. Anti-Alzheimer chemical constituents of Morus macroura Miq.: chemical profiling, in silico and in vitro investigations, Food Funct, 2022, Sep 7;12(17):8078-8089 PMID: 34286787
- Zsolt Datki, .et al. The interacting rotifer-biopolymers are anti- and disaggregating agents for human-type beta-amyloid in vitro, Int J Biol Macromol, 2022, Jan 7;201:262-269 PMID: 34999044
- Suresh K.Bowroju, .et al. Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer??s disease, Bioorg Med Chem, 2021, 45:116311
- Zsolt Datki, .et al. Exogenic production of bioactive filamentous biopolymer by monogonant rotifers, Ecotoxicol Environ Saf, 2021, Jan 15;208:111666 PMID: 33396176
Biological Activity
Amyloid beta (Aβ or Abeta) is a peptide of 36-C43 amino acids that is processed from the Amyloid precursor protein. Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 2.22 mL | 11.08 mL | 22.15 mL |
| 0.5 mM | 0.44 mL | 2.22 mL | 4.43 mL |
| 1 mM | 0.22 mL | 1.11 mL | 2.22 mL |
| 5 mM | 0.04 mL | 0.22 mL | 0.44 mL |
*The above data is based on the productmolecular weight 4514.08. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14075 |
|---|---|
| CAS No. | 107761-42-2 |
| Formula | C203H311N55O60S |
| M. Wt | 4514.08 |
| Purity | >98% |
| SMILES | [H]N[[email protected]@H](CC(O)=O)C(=O)N[[email protected]@H](C)C(=O)N[[email protected]@H](CCC(O)=O)C(=O)N[[email protected]@H](CC1=CC=CC=C1)C(=O)N[[email protected]@H](CCCNC(N)=N)C(=O)N[[email protected]@H](CC1=CNC=N1)C(=O)N[[email protected]@H](CC(O)=O)C(=O)N[[email protected]@H](CO)C(=O)NCC(=O)N[[email protected]@H](CC1=CC=C(O)C=C1)C(=O)N[[email protected]@H](CCC(O)=O)C(=O)N[[email protected]@H](C(C)C)C(=O)N[[email protected]@H](CC1=CNC=N1)C(=O)N[[email protected]@H](CC1=CNC=N1)C(=O)N[[email protected]@H](CCC(N)=O)C(=O)N[[email protected]@H](CCCCN)C(=O)N[[email protected]@H](CC(C)C)C(=O)N[[email protected]@H](C(C)C)C(=O)N[[email protected]@H](CC1=CC=CC=C1)C(=O)N[[email protected]@H](CC1=CC=CC=C1)C(=O)N[[email protected]@H](C)C(=O)N[[email protected]@H](CCC(O)=O)C(=O)N[[email protected]@H](CC(O)=O)C(=O)N[[email protected]@H](C(C)C)C(=O)NCC(=O)N[[email protected]@H](CO)C(=O)N[[email protected]@H](CC(N)=O)C(=O)N[[email protected]@H](CCCCN)C(=O)NCC(=O)N[[email protected]@H](C)C(=O)N[[email protected]@H]([[email protected]@H](C)CC)C(=O)N[[email protected]@H]([[email protected]@H](C)CC)C(=O)NCC(=O)N[[email protected]@H](CC(C)C)C(=O)N[[email protected]@H](CCSC)C(=O)N[[email protected]@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[[email protected]@H](C(C)C)C(=O)N[[email protected]@H](C(C)C)C(=O)N[[email protected]@H]([[email protected]@H](C)CC)C(=O)N[[email protected]@H](C)C(O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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