AM211 sodium is a selective and potent antagonist of the prostaglandin D2 receptor type 2 (DP2), exhibiting an IC50 of 4.9 nM for human DP2 and similar efficacy in mouse, guinea pig, and rat models with IC50s of 7.8 nM, 4.9 nM, and 10.4 nM, respectively. Its oral bioavailability makes it an important tool for studying the role of DP2 in various biological processes, including inflammation and allergic responses. AM211 sodium is suitable for research applications investigating the modulation of prostaglandin signaling pathways.
AM211 sodium is a selective and potent antagonist of the prostaglandin D2 receptor type 2 (DP2), exhibiting an IC50 of 4.9 nM for human DP2 and similar efficacy in mouse, guinea pig, and rat models with IC50s of 7.8 nM, 4.9 nM, and 10.4 nM, respectively. Its oral bioavailability makes it an important tool for studying the role of DP2 in various biological processes, including inflammation and allergic responses. AM211 sodium is suitable for research applications investigating the modulation of prostaglandin signaling pathways.
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