Aminooxy-PEG3-azide is a non-cleavable, three-unit PEG linker primarily used for the synthesis of antibody-drug conjugates (ADCs) and as a PEG-based linker in PROTAC development. This compound features an azide functionality that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a versatile tool for chemical biology applications.
Aminooxy-PEG3-azide is a non-cleavable, three-unit PEG linker primarily used for the synthesis of antibody-drug conjugates (ADCs) and as a PEG-based linker in PROTAC development. This compound features an azide functionality that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a versatile tool for chemical biology applications.
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