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XT-1

Catalog No.: A49239
Antimicrobial Peptide
XT-1 is an antimicrobial peptide derived from the skin secretions of Xenopus tropicalis. It exhibits potent activity against Staphylococcus aureus, Escherichia coli, and Candida albicans, with minimum inhibitory concentrations (MIC) of 5 μM, 6 μM, and 50 μM, respectively. XT-1 is valuable for research applications focusing on antimicrobial resistance and the development of novel therapeutic agents targeting pathogenic microorganisms.
XT-1 398143-78-7 Antimicrobial Peptide
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Research use only. We do not sell to patients.
Data Sheet SDS Compound Handling Instructions

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionXT-1 is an antimicrobial peptide derived from the skin secretions of Xenopus tropicalis. It exhibits potent activity against Staphylococcus aureus, Escherichia coli, and Candida albicans, with minimum inhibitory concentrations (MIC) of 5 μM, 6 μM, and 50 μM, respectively. XT-1 is valuable for research applications focusing on antimicrobial resistance and the development of novel therapeutic agents targeting pathogenic microorganisms.
Product Information
Catalog NumA49239
FormulaC134H227N37O31
Molecular Weight2852.47
CAS Number398143-78-7
SequenceGly-Phe-Leu-Gly-Pro-Leu-Leu-Lys-Leu-Ala-Ala-Lys-Gly-Val-Ala-Lys-Val-Ile-Pro-His-Leu-Ile-Pro-Ser-Arg-Gln-Gln
Sequence shorteningGFLGPLLKLAAKGVAKVIPHLIPSRQQ
SMILESC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]1N(C(CNC([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CN)=O)=O)CC(C)C)=O)=O)CCC1)CC(C)C)=O)CC(C)C)=O)CCCCN)=O)CC(C)C)=O)C)=O)C)=O)CCCCN)=O)=O)[C@H](C)C)=O)C)=O)CCCCN)=O)C(C)C)=O)[C@H](CC)C)(=O)N3[C@H](C(N[C@@H](CC4=CN=CN4)C(N[C@H](C(N[C@H](C(=O)N5[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(O)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CO)=O)CCC5)[C@H](CC)C)=O)CC(C)C)=O)=O)CCC3
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