Nocodazole

Catalog No.: A13219

microtubule inhibitor

Nocodazole

Nocodazole Chemical Structure

CAS NO. 31430-18-9

Nocodazole is a microtubule inhibitor; inhibits mitosis. Also inhibits autophagosome-lysosome fusion.

Availability: In stock

Package Price Qty
10 mg
$50.00
25 mg
$100.00
50 mg
$180.00
100 mg
$300.00
10mM * 1mL in DMSO
$60.00
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Biological Activity

Nocodazole is a microtubule inhibitor; inhibits mitosis. Also inhibits autophagosome-lysosome fusion.
Targets
Microtubules (Cell-free assay) Abl (Cell-free assay) Abl (E255K) (Cell-free assay) Abl (T315I) (Cell-free assay)
N/A0.21 μM0.53 μM0.64 μM
In vitro (25°C) DMSO 6 mg/mL (19.91 mM)
Water Insoluble
Ethanol Insoluble
In vivo 2% DMSO+30% PEG 300+2% Tween 80+ddH2O 1 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.19 mL 165.94 mL 331.87 mL
0.5 mM 6.64 mL 33.19 mL 66.37 mL
1 mM 3.32 mL 16.59 mL 33.19 mL
5 mM 0.66 mL 3.32 mL 6.64 mL

*The above data is based on the productmolecular weight 301.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13219
Actions Inhibitor
CAS No. 31430-18-9
Formula C14H11N3O3S
M. Wt 301.32
Purity >98%
SMILES COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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