Anti-inflammatory agent 104 is a potent anti-inflammatory compound that specifically inhibits TNF-α synthesis and release in the human macrophage cell line U937, with an IC50 value of 0.024 nM. This agent demonstrates significant biological activity by reducing eosinophil levels in rat lungs by 63%, making it a valuable tool for studying inflammatory responses and evaluating therapeutic strategies in related research applications.
Anti-inflammatory agent 104 is a potent anti-inflammatory compound that specifically inhibits TNF-α synthesis and release in the human macrophage cell line U937, with an IC50 value of 0.024 nM. This agent demonstrates significant biological activity by reducing eosinophil levels in rat lungs by 63%, making it a valuable tool for studying inflammatory responses and evaluating therapeutic strategies in related research applications.
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