Anti-inflammatory agent 11 targets and inhibits key inflammatory processes by suppressing inducible nitric oxide synthase (iNOS) expression. This compound demonstrates significant antimycobacterial activity against Mycobacterium tuberculosis strains H37Rv and M299, with minimum inhibitory concentrations (MIC50) of 1.3 μM and 6.9 μM, respectively. Additionally, it effectively reduces the production of pro-inflammatory cytokines such as TNF-α and IL-1β. Anti-inflammatory agent 11 is suitable for research in tuberculosis and related inflammatory diseases.
Anti-inflammatory agent 11 targets and inhibits key inflammatory processes by suppressing inducible nitric oxide synthase (iNOS) expression. This compound demonstrates significant antimycobacterial activity against Mycobacterium tuberculosis strains H37Rv and M299, with minimum inhibitory concentrations (MIC50) of 1.3 μM and 6.9 μM, respectively. Additionally, it effectively reduces the production of pro-inflammatory cytokines such as TNF-α and IL-1β. Anti-inflammatory agent 11 is suitable for research in tuberculosis and related inflammatory diseases.
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