Fig. 1 · Structure

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Anti-MRSA agent 11

Anti-MRSA Agent

Anti-MRSA Agent 11 functions as a potent antibacterial agent specifically targeting methicillin-resistant Staphylococcus aureus (MRSA). It demonstrates significant inhibitory activity against fluoroquinolone-sensitive strain USA500 and resistant isolate Mu50, with a minimum inhibitory concentration (MIC) of 0.39 μg/mL. This compound displays favorable pharmacokinetic properties, including a favorable in vivo half-life and an acceptable safety profile, making it a valuable tool for research into MRSA infections and antibiotic resistance mechanisms.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3029704-83-1
Applications Anti-MRSA Agent
Formula C24H18F2N4O3
Molecular Weight 448.42
SMILES
O=C(C1=CN(C2CC2)C3=CC(NC4=NC=CC(CC5=CC=C(C=C5F)F)=N4)=CC=C3C1=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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