Antibacterial Agent 102 is a potent antibacterial compound that exhibits significant in vitro and in vivo activity against Staphylococcus aureus, with minimum inhibitory concentrations (MICs) below 0.5 μg/mL. Additionally, it moderately inhibits the cytochrome P450 enzyme CYP3A4, with an IC50 value of 6.148 μM. This compound has demonstrated efficacy in reducing Methicillin-resistant Staphylococcus aureus (MRSA) loads in infected mice models, making it valuable for research into antibiotic resistance and therapeutic interventions.
Antibacterial Agent 102 is a potent antibacterial compound that exhibits significant in vitro and in vivo activity against Staphylococcus aureus, with minimum inhibitory concentrations (MICs) below 0.5 μg/mL. Additionally, it moderately inhibits the cytochrome P450 enzyme CYP3A4, with an IC50 value of 6.148 μM. This compound has demonstrated efficacy in reducing Methicillin-resistant Staphylococcus aureus (MRSA) loads in infected mice models, making it valuable for research into antibiotic resistance and therapeutic interventions.
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