Fig. 1 · Structure
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Antibiofilm agent-9
Antibiofilm Agent
Antibiofilm agent-9 is a pyrrolomycin derivative that targets bacterial biofilm formation. It demonstrates significant antibacterial activity against Bacillus anthracis, with a minimum inhibitory concentration (MIC) of 0.031 μg/mL. Additionally, Antibiofilm agent-9 shows impressive antibiofilm efficacy, achieving 84% biofilm inhibition at a concentration of 8.0 μg/mL after 24 hours. Its favorable pharmacokinetic properties in mouse models further support its potential applications in combating biofilm-associated infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2001602-07-7 |
| Applications | Antibiofilm Agent |
| Formula | C11H5BrCl2FNO2 |
| Molecular Weight | 352.97 |
| SMILES | O=C(C1=C(O)C(Cl)=CC(Cl)=C1)C2=CC(Br)=C(N2)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.