Fig. 1 · Structure
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Antimycin A2
Fungicide
Antimycin A2 is a potent inhibitor of the cytochrome b-c1 complex within the mitochondrial electron transport chain. By disrupting mitochondrial membrane potential and promoting the generation of reactive oxygen species (ROS), Antimycin A2 demonstrates bactericidal and piscicidal properties along with significant growth inhibitory effects on tumor cells, including inducing S-phase cell cycle arrest and apoptosis in HeLa cells. This compound is valuable for research applications in cervical cancer and fisheries management, and it can be isolated from the fermentation products of specific Streptomyces sp. strains.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 27220-57-1 |
| Applications | Fungicide |
| Formula | C27H38N2O9 |
| Molecular Weight | 534.60 |
| SMILES | CCCC(O[C@H]([C@H]1CCCCCC)[C@H](C)OC([C@@H](NC(C2=CC=CC(NC=O)=C2O)=O)[C@@H](C)OC1=O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.