Fig. 1 · Structure
Documents & Downloads
Antitubercular agent-19
Antitubercular Agent
Antitubercular Agent-19 is a potent antitubercular compound targeting Mycobacterium tuberculosis. It demonstrates remarkable activity against both the MTB H37Rv strain and multidrug-resistant Mycobacterium tuberculosis strains, with a minimum inhibitory concentration (MIC) of less than 0.016 µg/ml. Additionally, this compound exhibits low cytotoxicity while displaying a relatively high level of acute lethal toxicity in BALB/c mice, making it a valuable candidate for further research in tuberculosis treatment and drug resistance studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2248171-05-1 |
| Applications | Antitubercular Agent |
| Formula | C24H20F6N4O3S |
| Molecular Weight | 558.50 |
| SMILES | O=C1N=C(SC2=C(C=C(C=C12)C(F)(F)F)[N+]([O-])=O)N3CCC4(CN(C4)CC5=CC=C(C=C5)C(F)(F)F)CC3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.