Fig. 1 · Structure
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Antituberculosis agent-2
Antituberculosis Agent
Antituberculosis agent-2 is a targeted therapeutic compound effective against both drug-sensitive and multidrug-resistant strains of Mycobacterium tuberculosis. It exhibits notable anti-tuberculosis activity, demonstrated by minimum inhibitory concentrations (MIC) of 0.454, 1.757, and 1.644 μg/mL against M. tuberculosis strains H37Rv, 13946, and 14862, respectively. This compound possesses favorable stability in mouse and human microsomes, exhibits low cytotoxicity, and shows acceptable oral bioavailability, making it a valuable candidate for further research in tuberculosis treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2411741-01-8 |
| Applications | Antituberculosis Agent |
| Formula | C19H17NO4 |
| Molecular Weight | 323.34 |
| SMILES | O=C1C=C(C2=CC=C(O)C=C2)OC3=CC=C(O)C(CN4CCC4)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.