Fig. 1 · Structure
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Antituberculosis agent-5
Anti-tuberculous Agent
Antituberculosis agent-5 is a nitrofuranylamide derivative that specifically inhibits UDP-Gal mutase in Mycobacterium tuberculosis. It demonstrates significant anti-tuberculous activity, with an IC50 value of 99 μM for Glf activity inhibition and a minimal inhibitory concentration (MIC) of 1.6 μg/mL against tuberculosis. This compound serves as a valuable tool for research applications aimed at understanding and combating tuberculosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 313981-44-1 |
| Applications | Anti-tuberculous Agent |
| Formula | C13H12N2O5 |
| Molecular Weight | 276.24 |
| SMILES | O=C(C1=CC=C([N+]([O-])=O)O1)NCC2=CC=CC=C2OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.